|Statement||edited by Eric Fung.|
|The Physical Object|
|Pagination||xi, 287 p. :|
|Number of Pages||287|
Protein microarrays are chips harboring an array of proteins, peptides, antibodies, aptamers, or lysates embedded on its surface allowing researchers to study protein interactions, functions, or detect the presence of proteins in samples in a high-throughput manner. 27 Protein arrays are a powerful proteomics and interactomics tool and can be. Protein arrays make possible the detection and quantitation of many proteins simultaneously, thus enabling researchers to ask fundamental questions about biological processes and to discover biomarkers that can be used diagnostically. In Protein Microarrays: Methods and Protocols, expert researchers in the field present an up-to-date collection of robust strategies in the field of protein microarrays and summarize recent advantages in the field of printing technologies, the development of suitable surface materials, as well as detection and quantification : Hardcover. From disease marker identification to accelerated drug development, Protein Arrays, Biochips, and Proteomics offers a detailed overview of current and emerging trends in the field of array-based proteomics. This reference focuses on innovations in protein microarrays and biochips, mass spectrometry, high-throughput protein expression, protein Author: Joanna S. Albala.
Unlike antibody arrays (analytical microarrays), functional protein microarrays are made by spotting all of the proteins encoded by an organism and therefore are useful for characterization of protein functions, such as protein-protein binding, biochemical activity, enzyme-substrate relationships, and immune responses (Chen and Zhu, ; Poetz Cited by: Protein-Protein Interactions Small Molecule Interactions ATP ADP Enzymatic Assays 2. Functional Protein Microarrays Two Major Types of Protein Microarrays •Protein Biochemical Activities •Protein Modification and Regulation •Protein Pathways •Drug Discovery and DevelopmentFile Size: 2MB. Protein arrays are established as a powerful means to detect proteins and monitor their expression levels. Protein arrays have become one of the most active areas emerging in biotechnology. The objective behind protein array development is to achieve efficient and sensitive high throughput protein analysis. Cambridge Protein Arrays Ltd. - Your dedicated partner for protein array based screening projects. Established in Cambridge (UK) in , our academic roots are in protein arrays and protein affinity reagents. We have contributed to developing the area of protein arrays and are making our expertise available to you. We are European distributors.
Protein Arrays: Methods and Protocols is an introduction to protein array technology and its application to the multiplexed detection of proteins. Although protein array technology has some roots in gene array technology, it can only be described as a distant relative. Unlike DNA, with its. Protein Arrays: Methods and Protocols is an introduction to protein array technology and its application to the multiplexed detection of proteins. Although protein array technology has some roots in gene array technology, it can only be described as a distant relative. INTRODUCTION. Protein microarray technology has made enormous progress in the last decade, increasingly becoming an important research tool for the study and detection of proteins, protein-protein interactions and numerous other biotechnological applications (1–4).The use of protein microarrays has advantages over more traditional methods for the study of molecular by: This book provides practical guidance on all aspects of reverse phase protein array (RPPA) technology, which permits the quantification of protein levels in cell or tissue lysates. In addition, the latest results are presented from laboratories across the world where experts are successfully running the challenging RPPA data platform.